As for the Simple Representation case (SRC) mode, it is requested the following parameters: the quinones in model and the ones to serve as replacers, the model metabolite formats (ModelSEED, BiGG or KEGG), and the model in the SBML format. This description can be followed up right in the figure below.

Note that the compounds that will be swapped have to contain the correct database identifier in its annotation field in the SBML file. Otherwise, BOIMMG will not recognize the compounds.

Moreover, just in case, please check whether they are present in the database or not (search bar in the homepage).

As for the Redundant Representation case (RRC) mode, it is requested the following parameters: the generic lipids to be granulated and the respective components (fatty acids), whether the user wants to mix components or have always the same in each lipid species, the model metabolite formats (ModelSEED, BiGG or KEGG), and the model in the SBML format. This description can be followed up right in the figure bellow.

Note that the compounds that will be granulated have to contain the correct database identifier in its annotation field in the SBML file. Otherwise, BOIMMG will not recognize the compounds.

Moreover, just in case, please check whether they are present in the database or not (search bar in the homepage).

Furthermore, after the submission, a status page will be rendered, with information related to the stage in BOIMMG's granulation or swapping process. A progress bar will also be shown and updated. In the case of RRC, one of the messages regarding the generation of a given compound's network will possess a link to the compound being handled. Therein, information regarding the precursors being introduced will be rendered (figure below).